Transition in oscillatory behavior in mouse oocyte and mouse embryo through oscillatory spherical net model of mouse zona pellucida

Abstract

Zona pellucida, a 3D matrix that surrounds mammalian oocyte, dynamically changes its elasticity during the maturation and fertilization process. We consider fertilization as a biomechanical oscillatory phenomenon and hypothesized that mature oocyte and embryo are in different oscillatory states. Using an oscillatory spherical net model of mouse ZP [4], eigen circular frequencies of mouse oocyte and mouse embryo were calculated. Frequency analysis of circular frequencies of ZP under periodical external excitation force in the form of sperm cell impact was done for both states. To determine the conditions for dynamical absorption under impact of sperm cells on ZP of mouse oocyte and embryo, numerical analyses were done.