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dc.contributor.authorDragović, Brankoen
dc.contributor.authorDragovich, Alexandraen
dc.date.accessioned2020-12-11T13:04:47Z-
dc.date.available2020-12-11T13:04:47Z-
dc.date.issued2010-05-01en
dc.identifier.issn00104620en
dc.identifier.urihttp://researchrepository.mi.sanu.ac.rs/handle/123456789/4469-
dc.description.abstractThis paper presents the foundations of p-adic modelling in genomics. Considering nucleotides, codons, DNA and RNA sequences, amino acids and proteins as information systems, we have formulated the corresponding p-adic formalisms for their investigations. Each of these systems has its characteristic prime number used for construction of the related information space. Relevance of this approach is illustrated by some examples. In particular, it is shown that degeneration of the genetic code is a p-adic phenomenon. We have also put a forward a hypothesis on the evolution of the genetic code assuming that primitive code was based on single nucleotides and chronologically first four amino acids. This formalism of p-adic genomic information systems can be implemented in computer programs and applied to various concrete cases. © The Author 2007. Published by Oxford University Press on behalf of The British Computer Society. All rights reserved.en
dc.relation.ispartofComputer Journalen
dc.subjectEvolution of the genetic code | Genetic code | Genome | P-adic genomic space | P-adic modellingen
dc.titlep-adic modelling of the genome and the genetic codeen
dc.typeArticleen
dc.identifier.doi10.1093/comjnl/bxm083en
dc.identifier.scopus2-s2.0-77951903812en
dc.identifier.urlhttps://api.elsevier.com/content/abstract/scopus_id/77951903812en
dc.relation.firstpage432en
dc.relation.lastpage442en
dc.contributor.orcid#NODATA#en
dc.contributor.orcid#NODATA#en
dc.relation.issue4en
dc.relation.volume53en
item.cerifentitytypePublications-
item.fulltextNo Fulltext-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.openairetypeArticle-
item.grantfulltextnone-
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