Hedrih, Katica (Stevanović)
|Title:||Multi-parametric dependence of deformationwork of Zona Pelucida in fertilization process trough quasi-static continual shell-like ZP model||Journal:||Discontinuity, Nonlinearity, and Complexity||Volume:||6||Issue:||4||First page:||465||Last page:||476||Issue Date:||1-Jan-2017||Rank:||M53||ISSN:||2164-6376||DOI:||10.5890/DNC.2017.12.005||Abstract:||
Zona Pelucida (ZP) is highly specialized glycosylated and sulfated polymer gel that surrounds mammalian oocyte, exhibits elastic or viscoelastic properties and change of diameter in different maturation stages. In process of in vitro fertilization, sperm cells affect the external ZP surface and transfer certain amount of energy to the ZP structure that goes through the deformation work. ZP thickness and number of motile sperm cells are important factors that may influence the fertility. Using the quasi-static approximate ZP model in the form of hollow sphere the numerical analysis of how specific deformation work depends of different variables like: ZP thickness, specific point in ZP, external pressure that comes from sperm cells were done. According to the model, sperm that make pressure upon ZP surface are in the form of homogeny discrete continuum distribution in radial directions. For specific ZP point in the model, analytical expressions of component stresses and strains were obtained as well as deformations and volume dilatation in ZP. The results are discussed from biomechanical aspect of fertilization. Limitations of the model are also discussed.
|Keywords:||Plastic flow | Quasi-static continual shell-like ZP model | Specific deformation work | Strain | Stress | ZP thickness||Publisher:||L & H Scientific Publishing||Project:||Dynamics of hybrid systems with complex structures. Mechanics of materials.|
Show full item record
checked on Jan 29, 2023
checked on Jan 30, 2023
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.